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Advanced Reaction Kinetics Overview

Aug 9, 2025

Overview

This lecture introduces advanced kinetics, focusing on measuring reaction rates, interpreting rate equations, determining reaction orders, and understanding rate-determining steps using both continuous and initial rate experimental methods.

Measuring Rate of Reaction

  • Rate of reaction is defined as the change in concentration of product or reactant per unit time.
  • Standard unit for rate is mol dm⁻³ s⁻¹ (moles per cubic decimeter per second).
  • Six main methods for measuring rates: gas volume, mass change, color intensity (colorimetry), titration, pH change, and electrical conductivity.
  • Choice of method depends on the nature and precision required for the reaction.

Rate Equations and Rate Constants

  • Rate equation expresses rate as a function of reactant concentrations: rate = k[A]^m[B]^n.
  • 'k' is the rate constant; its unit depends on the overall order of the reaction.
  • First-order: rate ∝ [A]; Second-order: rate ∝ [A]^2; Zero-order: rate is independent of [A].
  • The unit of the rate constant varies (e.g., for second order: dm³ mol⁻¹ s⁻¹).

Reaction Order and Determination

  • Order indicates how the rate changes as concentrations of reactants change.
  • Overall order is the sum of the individual orders with respect to each reactant.
  • Orders are determined experimentally, not from the stoichiometric equation.
  • Zero order: no effect of concentration; First order: rate doubles if concentration doubles; Second order: rate quadruples if concentration doubles.

Rate Determining Step (RDS)

  • The slowest step in a reaction mechanism controls the overall reaction rate.
  • Only reactants in the RDS appear in the rate equation; zero-order reactants do not.
  • Mechanistic steps are inferred from experimental rate data.

Experimental Methods for Determining Order

Continuous Monitoring

  • Take samples from a single reaction over time, quench, and analyze (e.g., by titration).
  • Plot concentration vs. time; constant half-life signifies first-order, doubling half-life indicates second-order, straight line indicates zero-order.
  • Draw tangents to curves to find instantaneous rates.

Initial Rate Method

  • Repeat the reaction several times, varying the concentration of one reactant each time.
  • Compare changes in rate to changes in concentration to deduce orders.
  • Linear relationship (rate doubles with concentration) indicates first order; quadruple increase indicates second order.

Worked Example: NO + H₂ Reaction

  • Experimentally compare runs with varying NO and H₂ concentrations to determine orders: NO is second order (rate increases by 16 when [NO] increases by 4), H₂ is first order (consistent with observed rate changes).
  • Write rate equation: rate = k[NO]²[H₂].
  • Calculate k using experimental data and assign correct units based on overall reaction order.

Key Terms & Definitions

  • Rate of Reaction — change in concentration of a reactant or product per unit time.
  • Rate Equation — mathematical relationship linking rate to reactant concentrations.
  • Rate Constant (k) — proportionality constant in the rate equation.
  • Order of Reaction — power to which the concentration of a reactant is raised in the rate equation.
  • Half-life — time taken for concentration of a reactant to halve.
  • Rate Determining Step (RDS) — the slowest step in a reaction mechanism controlling the overall rate.

Action Items / Next Steps

  • Memorize the units for rate constants for different reaction orders.
  • Practice deriving rate constant units from rate equations.
  • Review and analyze sample data sets using both the continuous and initial rate method.
  • Complete core practical 9a and 9b as discussed.