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Muscle Contraction and Function

Jun 24, 2025

Overview

This lecture explains how skeletal muscles create and control movement, the mechanisms behind muscle contractions, and the functional grouping of muscles.

Structure and Function of Skeletal Muscles

  • There are 640 skeletal muscles in the human body, varying in size and function.
  • Skeletal muscles perform both powerful and delicate movements.
  • Muscles always pull; they never push.
  • Each skeletal muscle connects to bones via joints, with movement occurring as the insertion bone is pulled toward the origin.

Functional Groups of Muscles

  • Prime movers (agonists) are mainly responsible for a specific movement.
  • Antagonists reverse or oppose the movement of the prime mover.
  • Synergists assist prime movers with extra force or by stabilizing joints.
  • Muscle roles can switch depending on the movement being performed.

Muscle Contraction Mechanisms

  • A motor unit consists of a single motor neuron and all the muscle fibers it innervates.
  • Large motor units generate big, less precise movements; small units control fine, precise movements.
  • An action potential in a motor unit causes a twitch with three phases: latent, contraction, and relaxation.
  • Muscle force is graded by frequency of stimulation (temporal summation) and number of motor units activated (recruitment).

Graded Muscle Responses and Fatigue

  • Increasing stimulus frequency results in stronger twitches until maximum tension (tetanus) is reached.
  • Repeated strong contractions consume ATP, leading to muscle fatigue.
  • Recruitment follows the size principle: small units activate first, then larger ones for increased force.

Types of Muscle Contractions

  • Isotonic contractions occur when muscle tension changes muscle length (e.g., lifting an object).
  • Isometric contractions produce tension without changing muscle length (e.g., trying to lift an immovable object).

Key Terms & Definitions

  • Origin — the stationary bone attachment for a muscle.
  • Insertion — the movable bone attachment for a muscle.
  • Prime mover (agonist) — primary muscle for a specific action.
  • Antagonist — muscle that opposes the action of an agonist.
  • Synergist — muscle that aids a prime mover or stabilizes a joint.
  • Motor unit — a motor neuron and all muscle fibers it controls.
  • Twitch — a single contraction-relaxation cycle in a muscle fiber.
  • Temporal summation — increased force due to rapid, repeated stimulation.
  • Recruitment — increasing force by activating more motor units.
  • Isotonic contraction — muscle changes length during contraction.
  • Isometric contraction — muscle length stays the same during contraction.

Action Items / Next Steps

  • Review functional muscle groups and their roles.
  • Practice identifying examples of isotonic and isometric contractions.
  • Understand the phases of a muscle twitch and how force is graded.