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Difference Between Empirical and Molecular Formulas

Jun 8, 2025

Overview

This lecture explains the key difference between empirical and molecular formulas, describing what each type of formula represents and how to determine them.

Molecular Formula

  • The molecular formula shows the actual number of each type of atom in a compound.
  • Examples: Glucose (C6H12O6), Methane (CH4), and Hydrogen Peroxide (H2O2).
  • Indicates the real atomic ratio present in the compound.

Empirical Formula

  • The empirical formula is the simplest whole-number ratio of elements in a compound.
  • To find the empirical formula, divide all subscripts in the molecular formula by their greatest common factor.
  • Example: Glucose (C6H12O6) simplifies to CH2O as its empirical formula.
  • Methane’s molecular and empirical formulas are both CH4 because it’s already simplified.
  • Hydrogen peroxide (H2O2) simplifies to HO for its empirical formula.

Key Difference

  • The molecular formula gives the actual count of atoms; the empirical formula gives the simplest ratio.

Key Terms & Definitions

  • Molecular formula — the actual numbers of atoms of each element in a molecule.
  • Empirical formula — the simplest whole-number ratio of elements in a compound.
  • Subscript — the small number in a chemical formula showing the number of atoms of an element.

Action Items / Next Steps

  • Review the molar mass and mole concepts if necessary.
  • Practice simplifying molecular formulas to empirical formulas.