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Epithelial Tissue Overview

Jul 1, 2025

Overview

This lecture covers the four major tissue types in the body, with an in-depth focus on epithelial tissue, its characteristics, cell types, arrangements, and specific functions.

Four Major Tissue Types

  • Epithelial tissue forms protective coverings and linings.
  • Connective tissue provides support, structure, and nourishment.
  • Nervous tissue is responsible for transmitting signals.
  • Muscle tissue enables movement.

Epithelial Tissue Overview

  • Covers internal and external body surfaces, and lines cavities.
  • Forms the main component of glands.

Characteristics of Epithelial Tissue

  • Highly regenerative due to a high rate of cell division (mitosis).
  • Avascular (no blood vessels), but innervated (contains nerve endings).
  • Cells are tightly packed and anchored to a basement membrane.
  • Exhibits polarity: apical (top, exposed) and basal (bottom, attached) sides.
  • Specialized cell junctions like tight junctions and desmosomes connect cells.
  • Supported by underlying connective tissue for strength and nourishment.
  • Selectively permeable, allowing some substances to pass and blocking others.
  • May have microvilli (increase absorption) or cilia (move substances).

Epithelial Cell Types & Arrangements

  • Three major cell shapes: squamous (flat), cuboidal (cube-shaped), columnar (tall).
  • Two main arrangements: simple (one layer) and stratified (multiple layers).

General Functions of Epithelial Tissue

  • Gas exchange (e.g., oxygen and carbon dioxide).
  • Absorption of nutrients.
  • Secretion of substances (e.g., sweat, mucus).
  • Protection against pathogens and abrasion.

Types of Epithelial Cells (with Examples)

  • Simple Squamous: single layer, thin, allows gas exchange; found in lungs and capillaries.
  • Stratified Squamous: multiple layers, protects; found in skin (epidermis).
  • Simple Cuboidal: single layer, secretes and absorbs; found in kidneys.
  • Stratified Cuboidal: multiple layers, secretes; found in glands (rare).
  • Simple Columnar: single layer, increases absorption; found in stomach and intestines.
  • Pseudostratified Ciliated Columnar: appears layered but isn’t, has cilia, traps debris; found in respiratory system, trachea.
  • Transitional Epithelium: changes shape to stretch; found in the bladder.

Key Terms & Definitions

  • Avascular — lacking blood vessels.
  • Innervated — supplied with nerve endings.
  • Polarity — structural and functional difference between the top (apical) and bottom (basal) surfaces.
  • Basement Membrane — thin layer connecting epithelium to connective tissue.
  • Microvilli — surface projections that increase absorption.
  • Cilia — hair-like structures that move substances across the cell surface.
  • Desmosomes — cell junctions anchoring cells together.

Action Items / Next Steps

  • Review tissue types and main characteristics of epithelial tissue.
  • Memorize cell type shapes and typical locations.
  • Understand the general functions and arrangements of epithelial cells.