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Epithelial Tissue Identification

Sep 5, 2025

Overview

This lecture covers techniques to identify different types of epithelial tissue based on cell layer number and cell shape, with practical slide examples and naming conventions.

Identifying Epithelium: Key Questions

  • Ask: How many layers of cells are present?
  • Ask: What is the shape of the visible cells?

Types of Epithelium by Layers

  • One layer of cells is called "simple" epithelium.
  • Multiple layers of cells are called "stratified" epithelium.
  • Pseudostratified looks layered but all cells touch the basement membrane.

Types of Epithelium by Cell Shape

  • Squamous: flat cells ("squashed pancakes").
  • Cuboidal: cube-shaped cells with round nuclei.
  • Columnar: column-shaped cells with oval nuclei.

Special Identification Tips

  • Cuboidal vs. columnar: Check nuclei shape—round for cuboidal, oval for columnar.
  • Basement membrane: All epithelial tissue is attached to it.
  • Goblet cells (mucus-producing): Commonly found in simple columnar epithelium.
  • Cilia: Presence indicates ciliated pseudostratified columnar epithelium.
  • Pseudostratified epithelium has nuclei at different heights but is one layer.

Common Examples & Naming

  • Simple cuboidal: Single layer, square cells, round nuclei.
  • Simple columnar: Single layer, tall cells, oval nuclei, sometimes goblet cells.
  • Simple squamous: Single layer, flat cells, often seen in lung slides.
  • Stratified squamous: Multiple layers, flat cells at the top.
  • Transitional: Stratified, cells on top look bubbly, not clearly squamous, cuboidal, or columnar.
  • Ciliated pseudostratified columnar: One layer, varying cell heights, cilia, all cells touch basement membrane.

Key Terms & Definitions

  • Epithelium — tissue composed of one or more layers of cells covering surfaces or lining cavities.
  • Basement membrane — thin layer anchoring epithelium to underlying tissue.
  • Goblet cell — specialized cell that secretes mucus.
  • Cilia — hair-like structures on cell surface for movement.
  • Transitional epithelium — stratified epithelium with flexible, bubble-shaped surface cells, found in urinary tract.
  • Pseudostratified — appears layered but all cells touch the basement membrane.

Action Items / Next Steps

  • Practice identifying epithelial tissues under the microscope using layer count and cell shape.
  • Review definitions of key epithelium types.
  • Prepare for questions distinguishing closely related epithelial types.