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Comprehensive AP Biology Study Guide

Apr 25, 2025

AP Biology Exam Review & Study Plan

This guide provides a comprehensive review plan for the AP Biology exam, focusing on prioritizing study topics using the stoplight method, and covering key units and topics in the curriculum.

Study Plan

  • Stoplight Method:
    • Use three highlighters: red, green, yellow.
    • Green for well-known topics, Yellow for somewhat known, Red for unknown.
    • Prioritize studying: Red items first, then Yellow, and finally Green to keep topics fresh.

Unit 1: Chemistry of Life

  • Water and Hydrogen Bonding:
    • Water: polar molecule, forms hydrogen bonds.
    • Properties: cohesion, adhesion, surface tension, high specific heat.
    • Hydrogen bonding is crucial in DNA, RNA, proteins.
  • Elements of Life:
    • Monomers & Polymers: dehydration synthesis creates polymers; hydrolysis breaks them down.
    • Carbohydrates: Energy storage (monosaccharides), transport (disaccharides), structure (polysaccharides).
    • Lipids: Non-polar, fatty acids (saturated = solid, unsaturated = liquid).
    • Proteins: Diverse functions, made of amino acids (primary to quaternary structure).
    • Nucleic Acids: DNA (heredity, double-stranded, A-T and C-G), RNA (information transfer, catalysis).

Unit 2: Cell Structure and Function

  • Cell Types: Prokaryotic vs. Eukaryotic.
  • Cell Size: Surface area to volume ratio importance.
  • Membrane Structure: Fluid mosaic model, selective permeability, phospholipids, cholesterol.
  • Membrane Transport:
    • Passive transport: Simple & facilitated diffusion.
    • Active transport: ATP-powered pumps.
    • Osmosis: Water diffusion, hypotonic and hypertonic conditions.
  • Cellular Compartmentalization:
    • Endomembrane system: nuclear membrane, ER, Golgi.
    • Mitochondria & chloroplasts: endosymbiotic origin.

Unit 3: Cellular Energetics

  • Enzymes: Protein catalysts, specificity, denaturation.
  • Cell Energy:
    • Metabolic pathways (glycolysis, Krebs cycle, Calvin cycle).
    • ATP: Energy coupling.
  • Photosynthesis: Light reactions and Calvin cycle.
  • Cellular Respiration:
    • Stages: Glycolysis, link reaction, Krebs cycle, electron transport chain.
    • Anaerobic respiration and fermentation.

Unit 4: Cell Communication & Cell Cycle

  • Cell Communication: Signals & receptors, signal transduction, cellular responses.
  • Homeostasis & Feedback: Negative (e.g., glucose homeostasis) and positive feedback (e.g., childbirth).
  • Cell Cycle & Mitosis: Interphase, mitotic phases, checkpoints, cancer.

Unit 5: Heredity

  • Meiosis: Formation of haploid gametes, genetic diversity (crossing over, independent assortment).
  • Genetics: Mendel's laws, genetic crosses, linkage, non-nuclear inheritance.

Unit 6: Gene Expression & Biotechnology

  • DNA & RNA: Structure, replication, transcription, translation.
  • Gene Regulation: Operons, genomic equivalence, epigenetics.
  • Mutations: Types and effects on genetic code.
  • Genetic Engineering: Techniques, applications.

Unit 7: Evolution

  • Natural Selection & Speciation: Mechanisms, Hardy-Weinberg principle, evidence.
  • Phylogeny: Cladograms, evolutionary relationships.
  • Origin of Life: Abiotic synthesis, RNA world hypothesis.

Unit 8: Ecology

  • Responses to Environment: Case studies, analytical skills.
  • Energy Flow & Ecosystems: Metabolic rates, food webs, trophic levels.
  • Population Growth: Models, limiting factors.
  • Species Interactions: Competition, predation, mutualism.
  • Human Impact: Biodiversity loss, conservation.

Additional Resources

  • Learn-Biology.com: Interactive tutorials, practice questions, and study resources to prepare for the AP Bio exam.

Final Tips

  • Focus on understanding concepts rather than memorization.
  • Use practice exams to test knowledge and timing.
  • Stay organized and plan study sessions ahead.