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AP Biology Exam Preparation Guide

May 4, 2025

AP Biology Exam Review Plan

Study Strategy

  • Download Checklist: Available at apbiosuccess.com/checklist
  • Stoplight Method:
    • Green: Topics you know well
    • Yellow: Topics you are familiar with
    • Red: Topics you don’t know
  • Study Order: Start with red, then yellow, finish with green
  • Resources:
    • Tutorials and reviews on learn-biology.com
    • Science Music Videos channel for unit/topic reviews
    • Live reviews by Mr. W

Unit 1: Chemistry of Life

Topic 1.1: Water and Hydrogen Bonding

  • Water is polar and forms hydrogen bonds
  • Acts as a universal solvent
  • Key properties: cohesion, adhesion, surface tension, high specific heat

Topics 1.2 - 1.3: Elements and Molecules of Life

  • Monomers to polymers via dehydration synthesis, opposite through hydrolysis
  • Carbohydrates: Monosaccharides, disaccharides, polysaccharides
  • Lipids: Non-polar, fatty acids (saturated/unsaturated)
  • Proteins: Diverse functions, composed of amino acids
  • Nucleic Acids: DNA and RNA

Unit 2: Cell Structure and Function

Prokaryotic vs Eukaryotic Cells

  • Differences in size, structure, DNA packaging
  • Cell Size: Importance of surface area to volume ratio

Membrane Structure and Function

  • Selective permeability
  • Fluid mosaic model: phospholipids, proteins, cholesterol
  • Transport: Diffusion, facilitated diffusion, active transport
  • Osmosis: Movement of water, water potential

Cellular Compartmentalization

  • Endomembrane System: Nuclear membrane, ER, Golgi
  • Mitochondria & Chloroplasts: Endosymbiont theory

Unit 3: Cellular Energetics

Enzymes

  • Protein catalysts, lower activation energy
  • Specificity, sensitivity to environment
  • Inhibition: Competitive and non-competitive

Photosynthesis

  • Conversion of light energy into chemical energy
  • Light Reactions: Produce ATP, NADPH
  • Calvin Cycle: Carbon fixation

Cellular Respiration

  • Stages: Glycolysis, link reaction, Krebs cycle, electron transport chain
  • Anaerobic Respiration: Less ATP, fermentation

Unit 4: Cell Communication and Cycle

Cell Communication

  • Ligands and receptors
  • Signal Transduction: Reception, transduction, response

The Cell Cycle

  • Mitosis Phases: Interphase, prophase, metaphase, anaphase, telophase, cytokinesis
  • Regulation: Checkpoints, Cyclins, CDKs
  • Cancer: Unregulated cell division

Unit 5: Heredity

Meiosis and Genetic Variation

  • Germ cells create haploid gametes
  • Phases of Meiosis: Homologous pairs, sister chromatids
  • Mechanisms creating diversity: independent assortment, crossing over, fertilization

Genetic Principles

  • Mendelian genetics, monohybrid and dihybrid crosses
  • Dominant vs Recessive
  • Linked Genes: Inheritance patterns

Unit 6: Gene Expression

DNA Replication

  • Semi-conservative, involves helicase, DNA polymerase, etc.

Transcription and Translation

  • RNA synthesis, protein synthesis

Gene Regulation

  • Eukaryotic Gene Regulation: Acetylation and methylation, epigenetics
  • Mutations: Point and frameshift mutations

Unit 7: Evolution

Natural Selection and Population Genetics

  • Selection Types: Directional, stabilizing, disruptive
  • Hardy-Weinberg Principle: Allele frequency calculations

Evidence of Evolution

  • Fossils, homologous structures, molecular homologies

Speciation and Extinction

  • Biological species concept
  • Mechanisms: allopatric and sympatric speciation

Unit 8: Ecology

Responses to the Environment

  • Topics vary, analytical skills emphasized

Energy Flow and Ecosystems

  • Metabolic rate, trophic levels, pyramids of energy

Population and Community Ecology

  • Growth models, species interactions
  • Human impacts on biodiversity

Conclusion

  • Use resources like learn-biology.com to fill knowledge gaps
  • Live reviews and interactive content available for further study