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Polysaccharides Overview

Sep 5, 2025

Overview

This lecture explains polysaccharides, focusing on the structure and function of starch, glycogen, and cellulose, and compares their features and biological roles.

Polysaccharides: Definition and Roles

  • Polysaccharides are complex carbohydrates composed of many monosaccharides linked by glycosidic bonds.
  • Primary examples include starch, glycogen, and cellulose.
  • Main functions: energy storage and structural support in living organisms.

Starch: Structure and Function

  • Starch exists in two forms: amylose (unbranched) and amylopectin (branched); both are made of alpha-glucose monomers.
  • Amylose forms via 1,4 glycosidic bonds, leading to a coiled, helical structure.
  • Amylopectin has both 1,4 and 1,6 glycosidic bonds, creating side branches.
  • Starch stores glucose in plants; its insolubility and size prevent loss from cells.
  • Amylose's compact coil allows dense energy storage; amylopectin's branches aid rapid glucose release.

Glycogen: Structure and Function

  • Glycogen is the animal starch, also made of alpha-glucose monomers.
  • Structure is highly branched due to 1,4 and 1,6 glycosidic bonds.
  • Stores glucose in animals, with more branches for faster energy release due to higher activity levels.

Cellulose: Structure and Function

  • Cellulose consists of beta-glucose monomers forming long, unbranched chains.
  • Every second beta-glucose is flipped to enable 1,4 glycosidic bond formation.
  • Chains are cross-linked by hydrogen bonds into strong bundles (microfibrils and macrofibrils).
  • Provides structural support and rigidity in plant cell walls.

Comparison of Starch, Glycogen, and Cellulose

  • Starch (amylose, amylopectin) and cellulose are found in plants; glycogen in animals.
  • Starch and glycogen are made of alpha-glucose; cellulose of beta-glucose.
  • Amylose: only 1,4 bonds, unbranched. Amylopectin/glycogen: 1,4 and 1,6 bonds, branched. Cellulose: 1,4 bonds, unbranched, with cross-links.
  • In cellulose, adjacent beta-glucose units are inverted.

Key Terms & Definitions

  • Polysaccharide — Large carbohydrate made of many monosaccharides linked by glycosidic bonds.
  • Glycosidic bond — Covalent bond joining carbohydrate monomers.
  • Amylose — Unbranched starch polymer with 1,4 glycosidic bonds.
  • Amylopectin — Branched starch polymer with 1,4 and 1,6 bonds.
  • Glycogen — Highly branched animal carbohydrate from alpha-glucose.
  • Cellulose — Structural plant polysaccharide from beta-glucose, forming strong bundles.
  • Microfibril — Bundle of cellulose chains held by hydrogen bonds.

Action Items / Next Steps

  • Review differences between starch, glycogen, and cellulose structures.
  • Practice identifying types of glycosidic bonds in each polysaccharide.
  • Prepare for questions comparing functions and features of polysaccharides.