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Understanding the Bubonic Plague
Jun 3, 2025
Bubonic Plague (Black Death): What Is It, Symptoms, Treatment
Overview
What is the Bubonic Plague?
An infectious disease caused by the bacterium
Yersinia pestis
, affecting humans and animals.
Spread primarily by fleas traveling on rodents.
Bubonic plague is named for swollen lymph nodes (buboes), which can become large and ooze pus.
Other types of plague include:
Septicemic plague: Infection throughout the body.
Pneumonic plague: Infection in the lungs.
Historical Context
Also known as the Black Death, killing over 25 million people in the 14th century Europe.
Spread by rats on ships, leading to blackened gangrenous tissue, hence the name Black Death.
Current Occurrence
Still occurs worldwide, including the U.S., with 7 cases per year on average.
Mainly in Northern New Mexico, northern Arizona, southern Colorado, California, southern Oregon, and western Nevada.
Symptoms and Causes
Symptoms
Sudden high fever and chills.
Abdominal, arm, and leg pain.
Headaches.
Large swollen lymph nodes (buboes) leaking pus.
Septicemic plague may cause gangrenous blackened tissue and unusual bleeding.
Pneumonic plague may cause difficulty in breathing and coughing up blood.
Causes
Caused by the bacterium
Yersinia pestis
, spread by fleas.
Zoonotic disease, spreading between animals and humans.
Cats particularly vulnerable, spreading the infection to humans.
Rare human-to-human transmission, mainly in pneumonic plague cases.
Diagnosis and Tests
Diagnosis
Blood or tissue samples tested for presence of
Yersinia pestis
.
Management and Treatment
Treatment
Treatable and curable with antibiotics:
Ciprofloxacin, levofloxacin, moxifloxacin.
Gentamicin.
Doxycycline.
Hospitalization and possible isolation if diagnosed.
Consequences of Untreated Plague
Can lead to fatal outcomes.
Untreated, it may develop into septicemic or pneumonic plague.
Outlook / Prognosis
Prognosis
Good if treated promptly (within 24 hours of symptom development).
Recovery likely within one to two weeks.
High fatality rate if untreated.
Prevention
Preventive Measures
Make home and yard inhospitable to rodents and wild animals.
Use flea control products for pets.
Avoid letting pets who roam outside sleep in beds.
Wear protective clothing when handling dead animals.
Use insect repellent with DEET or permethrin in risky areas.
Living With
When to Contact Healthcare Provider
Develop symptoms like high fever, pain, swollen lymph nodes.
After exposure to flea bites or contact with infected individuals.
Additional Notes
Bubonic plague still present, particularly in rural U.S. areas.
Prevention focuses on avoiding fleas and protecting pets.
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View note source
https://my.clevelandclinic.org/health/diseases/21590-bubonic-plague