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Understanding the Bubonic Plague

Jun 3, 2025

Bubonic Plague (Black Death): What Is It, Symptoms, Treatment

Overview

What is the Bubonic Plague?

  • An infectious disease caused by the bacterium Yersinia pestis, affecting humans and animals.
  • Spread primarily by fleas traveling on rodents.
  • Bubonic plague is named for swollen lymph nodes (buboes), which can become large and ooze pus.
  • Other types of plague include:
    • Septicemic plague: Infection throughout the body.
    • Pneumonic plague: Infection in the lungs.

Historical Context

  • Also known as the Black Death, killing over 25 million people in the 14th century Europe.
  • Spread by rats on ships, leading to blackened gangrenous tissue, hence the name Black Death.

Current Occurrence

  • Still occurs worldwide, including the U.S., with 7 cases per year on average.
  • Mainly in Northern New Mexico, northern Arizona, southern Colorado, California, southern Oregon, and western Nevada.

Symptoms and Causes

Symptoms

  • Sudden high fever and chills.
  • Abdominal, arm, and leg pain.
  • Headaches.
  • Large swollen lymph nodes (buboes) leaking pus.
  • Septicemic plague may cause gangrenous blackened tissue and unusual bleeding.
  • Pneumonic plague may cause difficulty in breathing and coughing up blood.

Causes

  • Caused by the bacterium Yersinia pestis, spread by fleas.
  • Zoonotic disease, spreading between animals and humans.
  • Cats particularly vulnerable, spreading the infection to humans.
  • Rare human-to-human transmission, mainly in pneumonic plague cases.

Diagnosis and Tests

Diagnosis

  • Blood or tissue samples tested for presence of Yersinia pestis.

Management and Treatment

Treatment

  • Treatable and curable with antibiotics:
    • Ciprofloxacin, levofloxacin, moxifloxacin.
    • Gentamicin.
    • Doxycycline.
  • Hospitalization and possible isolation if diagnosed.

Consequences of Untreated Plague

  • Can lead to fatal outcomes.
  • Untreated, it may develop into septicemic or pneumonic plague.

Outlook / Prognosis

Prognosis

  • Good if treated promptly (within 24 hours of symptom development).
  • Recovery likely within one to two weeks.
  • High fatality rate if untreated.

Prevention

Preventive Measures

  • Make home and yard inhospitable to rodents and wild animals.
  • Use flea control products for pets.
  • Avoid letting pets who roam outside sleep in beds.
  • Wear protective clothing when handling dead animals.
  • Use insect repellent with DEET or permethrin in risky areas.

Living With

When to Contact Healthcare Provider

  • Develop symptoms like high fever, pain, swollen lymph nodes.
  • After exposure to flea bites or contact with infected individuals.

Additional Notes

  • Bubonic plague still present, particularly in rural U.S. areas.
  • Prevention focuses on avoiding fleas and protecting pets.