TRT and Hormone Optimization Lecture Notes

Introduction

• Speaker: Steven Devos
• Guest: Gil T
• Topic: Basic concepts of TRT (Testosterone Replacement Therapy) and hormone optimization.

Key Concepts

• Dosage Calculations:

  • Differentiation between mass and volume is crucial.
  • Volume (
    • e.g., 0.5 cc) is not a dose; it's the volume of fluid.
  • Dose is measured in mass, e.g., milligrams (mg).

• Concentration:

  • Expressed as mass per volume (e.g., mg/ml).
  • Example: Testosterone Cypionate (common in the US) is 200 mg/ml.
  • 1 cc = 1 ml; thus, 200 mg per ml of testosterone means 1 cc (or 1 ml) = 200 mg.

Volume Measurement

• Insulin Syringes:
  • Typically come in 100, 50, or 30 units.
  • 100 units = 1 ml.
  • 25 units = 0.25 ml, 50 units = 0.5 ml, and 100 units = 1 ml.
• Volume vs Dose:
  • Dosage should be expressed in mg, not ml or cc.

Unit Conversion

• Laboratory Units:

  • US: Nanograms per deciliter (ng/dL).
  • Europe: Nanomoles per liter (nmol/L).
  • Conversion can be easily done using online tools like the Google calculator.

• Common Conversion Errors:

  • LabCorp error: Reports free testosterone in ng/dL but labels as pg/ml.
  • Correct understanding is crucial for accuracy.

Closing Notes

• Additional Resources:
  • Amazon links for products related to hormone optimization.
  • Encouraged to subscribe and view more content for comprehensive understanding.

Conclusion

• Emphasized the importance of understanding concentration and dosage in TRT.
• Recommended using reliable conversion tools to avoid errors in interpreting lab results.