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Assessment of Altered Mental Status

Sep 4, 2025

Overview

This lecture covers a systematic approach to assessing patients with altered mental status, introducing key mnemonics to guide paramedics through essential differential diagnoses and interventions.

Assessment Mnemonics for Altered Mental Status

Evans's 3 S's Mnemonic

  • The three primary causes to consider are Stroke, Sepsis, and Sugar (hypo/hyperglycemia).
  • For stroke, perform a stroke scale assessment.
  • For sepsis, look for fever, tachycardia, and hypotension; common infection sources are pneumonia and urinary tract infection (UTI).
  • For sugar, check the patient's blood glucose level.
  • An additional "bonus S": Seizure—consider seizure activity or history, including possible causes like alcoholism.

N-O-T Mnemonic

  • N stands for Narcan—consider opiate or other drug overdoses and toxic emergencies.
  • O stands for Oxygen—assess for hypoxia; give supplemental oxygen if SpO2 is below 94%.
  • T stands for Trauma—look for signs of hidden trauma, such as head injury or internal bleeding, especially if not obvious on initial exam.

Clinical Decision Steps

  • If all assessments (vital signs, glucose, stroke scale, physical exam) are normal, consider internal or metabolic causes requiring hospital evaluation.
  • Early identification and communication with the hospital are crucial for life-threatening conditions.

Key Terms & Definitions

  • Altered Mental Status — Any change in a patient’s level of consciousness or cognitive function.
  • Stroke — Loss of brain function due to interrupted blood supply, assessed with stroke scales.
  • Sepsis — Life-threatening organ dysfunction from an overwhelming infection, often with fever, tachycardia, and hypotension.
  • Hypoglycemia/Hyperglycemia — Abnormally low or high blood glucose levels affecting mental status.
  • Seizure — Sudden, uncontrolled electrical disturbance in the brain, potentially causing confusion or altered consciousness.
  • Narcan (Naloxone) — Medication used to reverse opioid overdoses.
  • Hypoxia — Low blood oxygen level, causes confusion and other symptoms.
  • Trauma — Physical injury that may not be apparent, including internal bleeding or head injury.

Action Items / Next Steps

  • Practice using the "3 S's" and "N-O-T" mnemonics during patient assessments.
  • Review common sources and signs of infection, stroke, and trauma.
  • Ensure competence with vital sign measurement and glucose checks.
  • Prepare for possible scenarios involving overdose, hypoxia, or hidden trauma.