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AI in Patient Portal Messaging: Risks and Opportunities
May 24, 2025
Opportunities and Risks of AI in Patient Portal Messaging in Primary Care
Introduction
Increased adoption of patient portals and telemedicine post-pandemic has resulted in a surge in patient portal messaging.
Primary care physicians (PCPs) face increased workloads due to electronic health record (EHR) tasks, leading to burnout.
Strategies to manage inbox overload have had limited success, including message length limits, billing for messages, and limiting message exchanges.
Generative AI, using large language models (LLMs), is being explored to draft automatic message responses to reduce workload.
Early results indicate a reduction in cognitive burden but no significant time reductions.
Risks include LLMs introducing inaccurate or inappropriate information, possibly affecting patient safety.
Study Objectives
Primary Objective
: Determine how PCPs address errors in AI-generated draft responses.
Secondary Objective
: Assess PCP perspectives on AI-generated responses.
Results
Study involved 20 participants, mostly female attending physicians with an average of 14.75 years post-medical school.
Participants missed correcting errors in AI drafts frequently, with a high likelihood of errors reaching patients.
Survey Responses
Participants held favorable views of AI drafts, reporting reduced cognitive workload and trust in AI tools.
Discussion
AI-generated drafts can pose safety risks due to hallucinations and outdated information.
Current AI implementations in healthcare outpace understanding of their safety.
Low rates of error detection by PCPs in AI drafts raise safety concerns.
Possible cognitive biases affecting error detection include functional fixedness, confirmation bias, automation complacency, and automation bias.
Recommendations include design improvements, technological advancements, and human review guidelines.
Limitations
Lack of full patient records for participants.
Remote study setting may have introduced distractions.
No control group for error rate comparison without AI assistance.
Limited diversity of message content covered.
Use of non-validated survey instruments.
Methods
Study approved by MedStar Health IRB; informed consent obtained.
Participants responded to 18 PPMs with AI-generated drafts in a simulated environment.
AI drafts reviewed by experienced PCPs to identify errors.
Data and Code Availability
Datasets and analysis code available upon request from the corresponding author.
Conclusions
AI drafts offer benefits in reducing cognitive load but present significant safety concerns.
A need for further research into AI error types, cognitive biases, and effective integration into clinical practice.
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View note source
https://www.nature.com/articles/s41746-025-01586-2