Understanding Pregnancy Physiological Changes

Dec 18, 2024

Physiology of Pregnancy

Case Study

  • Patient: Jenny, 25-year-old, Gravita 1 para-zero female
  • Gestation: 34 weeks
  • Symptoms: Increased difficulty in taking deep breaths, no shortness of breath on exertion, no chest pain
  • History: Uncomplicated pregnancy, no medical problems
  • Discussion Point: What is the most likely cause of her difficulty in breathing?

Physiological Changes During Pregnancy

Eight systems to focus on:

  1. Cardiovascular
  2. Hematologic
  3. Respiratory
  4. Gastrointestinal
  5. Renal
  6. Metabolic
  7. Endocrine
  8. Anatomic changes

Cardiovascular System

  • Anatomical Changes:
    • Heart is displaced left and upward, rotated on its long axis
    • Location for heart sound auscultation changes
  • Physiological Changes:
    • Systemic Vascular Resistance: Decreases
    • Blood Pressure: Decreases in first and second trimesters
    • Mean Arterial Pressure: Decreases
    • Heart Rate: Increases
    • Cardiac Output: Increases by 15% to 40% in the first trimester; more during labor

Hematologic System

  • Blood Volume: Increases 40% to 45%
    • Increase in erythrocytes and plasma
    • Leads to physiologic anemia
  • Iron Requirements: Increase, may require supplementation
  • Immune System: Blunted, pregnancy is an immunodeficient state
  • Hypercoagulability:
    • Increased risk for deep vein thrombosis (DVT) and pulmonary embolism
    • Important in context of C-sections and surgery

Respiratory System

  • Anatomical Changes:
    • Diaphragm rises by 4 cm due to enlarging uterus
  • Physiological Changes:
    • Functional Residual Capacity: Decreases
    • Total Lung Volume: Does not change
    • Expiratory Residual Volume & Residual Volume: Decrease
    • Tidal Volume & Minute Ventilation: Increase

Question

  • Question: During pregnancy, which physiologic changes happen within the pulmonary system?
    • A) Total lung capacity decreases
    • B) Inspiratory capacity decreases
    • C) Residual volume decreases
    • D) None of the above
  • Answer: C) Residual volume decreases due to uterine compression and diaphragm displacement

Summary

  • Pregnancy affects multiple body systems, with significant cardiovascular, hematologic, and respiratory changes.
  • Understanding these changes helps address symptoms and risks related to pregnancy, such as Jenny's breathing difficulty.