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Pregnancy Development Timeline

Jul 22, 2025

Overview

This lecture covers fetal development and maternal changes during pregnancy, week by week, from conception through the end of the third trimester.

First Trimester (Weeks 1–13)

  • Weeks 1–2: Egg develops and implants in the uterus.
  • Week 3: Baby is a blastocyst, several hundred rapidly dividing cells.
  • Week 4: Embryo consists of two layers; primitive placenta forms; length 0.2 mm.
  • Week 5: Embryo grows quickly; pregnancy symptoms start; length 2 mm.
  • Week 6: Facial features begin forming; morning sickness possible; heart activity visible; length 4 mm.
  • Week 7: Limb buds form; uterus doubles in size; length 1 cm; heart rate 145–180 BPM.
  • Week 8: Baby is moving; decisions about prenatal tests may begin; length 1.6 cm; weight 1 g.
  • Week 9: Baby looks more human; waist may thicken; length 2.3 cm; weight 2 g.
  • Week 10: Major organs and structures complete; length 3.1 cm; weight 4 g.
  • Week 11: Hands open/close; tooth buds form; length 4.1 cm; weight 10 g.
  • Week 12: Toes curl; brain and kidney development; length 5.4 cm; weight 14 g.
  • Week 13: Fingerprints form; nearly 3 in long; length 7.4 cm; weight 23 g.

Second Trimester (Weeks 14–27)

  • Week 14: Baby's facial expressions visible; energy improves; length 8.7 cm; weight 43 g.
  • Week 15: Baby senses light, forms taste buds; stuffy nose possible; length 10.1 cm.
  • Week 16: Growth spurt begins; length 11.6 cm; weight 100 g.
  • Week 17: Skeleton ossifies; umbilical cord thickens; length 13 cm; weight 140 g.
  • Week 18: Genitals visible on ultrasound; increased appetite; length 14.2 cm; weight 190 g.
  • Week 19: Baby may hear; round ligament pain possible; length 15.3 cm; weight 240 g.
  • Week 20: Halfway point; baby swallows, makes meconium; length 16.4 cm; weight 300 g.
  • Week 21: Baby movement felt; eyebrows develop; length 26.7 cm; weight 360 g.
  • Week 22: Baby resembles a newborn; belly size increases; length 27.8 cm; weight 430 g.
  • Week 23: Baby feels mother's motion; swelling in ankles/feet; length 28.9 cm; weight 501 g.
  • Week 24: Uterus soccer ball size; length 30 cm; weight 600 g.
  • Week 25: Baby gains fat, more hair; mother may notice hair changes; length 34.6 cm; weight 660 g.
  • Week 26: Baby practices breathing with amniotic fluid; length 35.6 cm; weight 760 g.
  • Week 27: Hiccups, eye opening, finger sucking; length ~36.6 cm; weight 875 g.

Third Trimester (Weeks 28–40)

  • Week 28: Baby perceives light; length 37.6 cm; weight 1050 g.
  • Week 29: Muscles/lungs mature; head grows; length 38.6 cm; weight 1153 g.
  • Week 30: Baby almost 3 lbs; mood swings and fatigue common; length 39.9 cm; weight 1319 g.
  • Week 31: Strong kicks, Braxton Hicks contractions; length 41.1 cm; weight 1502 g.
  • Week 32: Baby gains fat; possible heartburn and breathlessness; length 42.4 cm; weight 1720 g.
  • Week 33: Over 4 lbs; sleep discomfort increases; length 43.7 cm; weight 1918 g.
  • Week 34: CNS and lungs mature; dizziness, fatigue possible; length 45 cm; weight 2146 g.
  • Week 35: Baby movement less dramatic; length 46.2 cm; weight 2383 g.
  • Week 36: Baby drops into pelvis; gains about 1 oz/day; length 47.4 cm; weight 2622 g.
  • Week 37: Brain/lungs mature; more discharge/contractions; length 48.6 cm; weight 2859 g.
  • Week 38: Firm grasp; monitor for preeclampsia; length 49.8 cm; weight 3083 g.
  • Week 39: Full-term; contact healthcare provider if water breaks; length 50.7 cm; weight 3188 g.
  • Week 40: Due date; labor starts or induction considered; length 51.2 cm; weight 3462 g.

Key Terms & Definitions

  • Blastocyst — Early-stage embryo, a ball of cells formed after fertilization.
  • Embryo — Developing baby from implantation to 8 weeks.
  • Placenta — Organ supplying oxygen/nutrients to the embryo or fetus.
  • Meconium — Baby's first stool, composed of swallowed materials.
  • Braxton Hicks contractions — Irregular, usually painless uterine contractions in late pregnancy.
  • Preeclampsia — Pregnancy complication causing high blood pressure.

Action Items / Next Steps

  • Review weekly fetal development milestones.
  • Monitor for signs of preeclampsia and labor in late pregnancy.
  • Prepare questions for healthcare provider on upcoming prenatal tests.