🦴

Study on Hip Joint Disease in Psoriatic Arthritis

May 1, 2025

Hip Joint Disease in Psoriatic Arthritis: Risk Factors and Natural History

Overview

  • This document discusses the study on hip joint disease in patients with psoriatic arthritis (PsA), focusing on risk factors and the natural progression of the disease.
  • Study conducted by C. Michet, T. Mason, and M. Mazlumzadeh from the Division of Rheumatology at Mayo Clinic.

Patients and Methods

  • Sample Size: 504 patients diagnosed with PsA according to ESSG criteria.
  • Follow-Up Duration: Mean follow-up period was 5.7 years.
  • Age of Onset: Mean age at onset of psoriasis was 32 years; mean age at onset of PsA was 39 years.
  • Patterns of PsA:
    • Oligoarticular pattern was most common at onset (49%).
    • Polyarticular pattern was most common at latest examination (65%).
    • Sacroiliitis or spondylitis diagnosed in 94 patients (18.7%).

Results

  • Development of Hip Arthropathy:
    • 32 patients (6.3%) developed psoriatic hip arthropathy.
    • 26 of these 32 patients (81%) also had sacroiliitis or spondylitis.
    • In 41% of these cases, the hip joint became affected within 1 year of PsA onset.
    • Younger patients more commonly developed hip disease.
    • Sex, arthritis pattern, psoriasis duration, and other factors like dactylitis or enthesitis were not linked to increased hip disease risk.
  • Progression and Treatment:
    • 17 patients were followed up, and 9 required hip arthroplasty.
    • 50% of these patients underwent arthroplasty within 5 years of onset of hip pain.

Conclusions

  • Psoriatic hip arthropathy is relatively rare in PsA.
  • It is associated with earlier arthritis onset and linked with psoriatic spondylitis.
  • Bilateral hip involvement and rapid progression to hip arthroplasty are common observations.

Additional Notes

  • The full text of the study is available as a PDF.
  • A case illustrating established hip arthropathy in a patient with a history of psoriasis and PsA is included in the study.
  • This study is published in the Annals of the Rheumatic Diseases, courtesy of BMJ Publishing Group.