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Digestive System Overview

Jun 24, 2025

Overview

This lecture explains the structure and function of the human digestive system, detailing each stage as food transforms into energy and nutrients.

Structure of the Digestive System

  • The digestive system processes between 1-2.7 kg of food per person daily.
  • It comprises ten organs, nine meters in length, and over 20 specialized cell types.
  • Four main components: gastrointestinal (GI) tract, accessory organs (pancreas, gallbladder, liver), regulatory systems (enzymes, hormones, nerves, blood), and the mesentery tissue.
  • The GI tract has an internal surface area of 30–40 m².

Stages of Digestion

  • Digestion begins with saliva production in anticipation of food, creating about 1.5 liters daily.
  • Chewing and saliva turn food into a bolus and begin starch breakdown via enzymes.
  • The bolus travels down the esophagus via peristalsis (muscular contractions).
  • In the stomach, acids and enzymes break down proteins, and hormones stimulate accessory organs.
  • After roughly 3 hours, the bolus becomes chyme and moves into the small intestine.

Small Intestine Function

  • Bile from the liver and gallbladder digests fats in the duodenum.
  • Pancreatic and intestinal juices further break down fats, proteins, and carbohydrates.
  • Villi in the jejunum and ileum increase absorption surface for nutrients to enter the bloodstream.

Large Intestine and Waste Removal

  • Fiber, water, and dead cells enter the colon (large intestine).
  • The colon absorbs remaining water, forming stool.
  • Stool is stored in the rectum until expelled through the anus.
  • The full digestive process takes about 30–40 hours.

Key Terms & Definitions

  • Bolus — moist lump of chewed food ready to be swallowed.
  • Peristalsis — series of muscular contractions moving food through the GI tract.
  • Chyme — frothy liquid form of food after stomach processing.
  • Bile — digestive fluid from the liver/gallbladder that breaks down fats.
  • Villi — small projections lining the small intestine to aid nutrient absorption.
  • Stool — waste mass formed in the colon, expelled from the body.

Action Items / Next Steps

  • Review the stages of digestion and key organ functions for better understanding.
  • Prepare any questions about the digestive process for discussion.