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Understanding the Meiosis Process

Apr 24, 2025

Phases of Meiosis

Introduction to Meiosis

  • Meiosis, also known as reduction division, is the process of cell division that produces gametes (sex cells like sperm and egg cells).
  • Meiosis consists of two stages of cell division: Meiosis I and Meiosis II.

Meiosis I

  • Prophase I

    • Begins with a diploid cell.
    • Chromatin contains two uncoiled chromosome sets (from each parent).
    • DNA replicates and condenses into X-shaped chromosomes.
    • Chromosomes pair up (synapsis) with homologous chromosomes, forming a tetrad (4 chromatids).
    • Crossing over occurs, exchanging alleles between chromatids, leading to genetic variety.
    • Nuclear membrane disappears; centrioles move to opposite ends; spindle fibers form.
  • Metaphase I

    • Homologous chromosomes line up at the equator.
    • Chromosomes attach to spindle fibers from opposite poles.
  • Anaphase I

    • Homologous chromosomes in tetrads separate and move to opposite poles.
  • Telophase I

    • Each pole has one chromosome from each homologous pair.
    • Chromosomes consist of non-identical sister chromatids due to crossing over.
    • Nuclear membrane reforms; spindle fibers disappear; cytokinesis occurs.
    • Ends with two genetically different haploid daughter cells.

Meiosis II

  • Prophase II

    • No DNA replication occurs before.
    • Nuclear membrane disappears; spindle fibers form from centrioles.
  • Metaphase II

    • Chromosomes line up at the equator.
    • Attach to spindle fibers from both poles.
  • Anaphase II

    • Sister chromatids separate and move to opposite poles, now called chromosomes.
  • Telophase II

    • Spindle fibers disappear; nuclear membranes reform; cytokinesis occurs.
    • Results in four genetically different haploid daughter cells.

Key Points

  • Meiosis starts with a diploid cell and produces genetically different haploid gametes.
  • Consists of two stages: Meiosis I (separation of homologous chromosomes) and Meiosis II (separation of sister chromatids).
  • Crossing over during Prophase I results in genetic variation in gametes.
  • All gametes produced by meiosis are haploid.