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Understanding Dyshidrosis: Symptoms and Causes

Apr 18, 2025

Dyshidrosis: Symptoms and Causes

Overview

  • Dyshidrosis, also known as dyshidrotic eczema or pompholyx, is a skin condition.
  • Characterized by small, fluid-filled blisters on palms, sides of fingers, and sometimes soles of feet.
  • Blisters are itchy and last a few weeks, often recurring.
  • Treatment usually involves prescription steroid creams, light therapy, or oral/injection medications.
  • Severity of symptoms determines treatment.

Symptoms

  • Painful, itchy, fluid-filled blisters on fingers, palms, or feet soles.
  • Blisters are small, about the width of pencil lead, and appear in clusters.
  • Severe cases can involve larger blisters due to merging.
  • Blisters eventually dry and flake off.
  • Condition may recur regularly over months or years.

When to See a Doctor

  • See a doctor if the rash is severe, persists, or spreads beyond hands and feet.

Causes

  • Exact cause unknown.
  • Often occurs alongside atopic dermatitis (eczema) and allergies such as hay fever or glove allergy.
  • Not contagious.

Risk Factors

  • Stress: Occurs more frequently during emotional or physical stress.
  • Metal Exposure: Cobalt and nickel exposure, often industrial.
  • Sensitive Skin: Rash from certain irritants increases risk.
  • Atopic Dermatitis: Those with this condition may develop dyshidrosis.

Complications

  • Generally an itchy inconvenience.
  • Pain and itching can limit hand/foot use.
  • Intense scratching can lead to bacterial infection.
  • Postinflammatory hyperpigmentation may occur, especially in people with brown or Black skin, but typically resolves over time.

Prevention

  • No known prevention.
  • Manage stress and avoid metal salts like cobalt and nickel.
  • Adopt good skin care practices:
    • Use mild, non-soap cleansers and lukewarm water.
    • Dry hands well.
    • Apply moisturizer twice daily.
    • Wear gloves to prevent irritation; try cotton gloves if allergic to others.

Note

The content is written by Mayo Clinic Staff and references several sources including clinical dermatology resources and expert opinions.