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Heart Anatomy and Function

Aug 11, 2025

Overview

This lecture covers the anatomy, chambers, valves, blood flow, conduction system, and nerve supply of the heart, emphasizing structure-function relationships and clinical relevance.

Anatomical Position and External Features

  • The heart is a muscular organ located in the mediastinum between the lungs.
  • It is covered by the pericardium, which separates it from other mediastinal structures.
  • The heart has four sides, a base (posterior), and an apex (anterior/left).
  • Borders: superior (atria), inferior (right and part of left ventricle), right (right atrium), left (left ventricle and left auricle).
  • Heart silhouette can be seen on a chest X-ray; right border (right atrium), left border (left ventricle/auricle).

Chambers of the Heart

  • The heart has four chambers: right atrium, right ventricle, left atrium, and left ventricle.
  • Right atrium receives deoxygenated blood from the superior/inferior vena cava and coronary sinus.
  • Left atrium receives oxygenated blood from the four pulmonary veins.
  • Right and left ventricles are separated by the interventricular septum.

Valves and Blood Flow

  • Blood flows from right atrium → tricuspid valve → right ventricle → pulmonary semilunar valve → pulmonary trunk → lungs.
  • Oxygenated blood returns via pulmonary veins → left atrium → mitral (bicuspid) valve → left ventricle → aortic semilunar valve → aorta → body.
  • Tricuspid valve (three cusps), mitral valve (two cusps), both anchored by chordae tendineae to papillary muscles.
  • Semilunar valves (pulmonary, aortic) have three cusps, no chordae tendineae; prevent backflow during relaxation.

Internal Structure Details

  • Right atrium: smooth posterior (sinus venarum), rough anterior (pectinate muscles), separated by crista terminalis.
  • Right ventricle: trabeculae carneae, papillary muscles, moderator band; outflow part is the conus arteriosus.
  • Interventricular septum: muscular and thin membranous parts.
  • Left atrium: mostly smooth, pectinate muscles in auricle, no valves in pulmonary veins.
  • Left ventricle: thickest wall, fine trabeculae carneae, aortic vestibule, mitral and aortic valves.

Conducting System and Nerve Supply

  • SA node (pacemaker) sets heart rhythm, located at junction of superior vena cava and right atrium.
  • AV node receives impulse, passes to AV bundle, then right/left bundle branches and Purkinje fibers for coordinated ventricular contraction.
  • Cardiac plexus provides sympathetic (increases rate/force) and parasympathetic (decreases rate) innervation.

Key Terms & Definitions

  • Pericardium — Membrane covering the heart.
  • Auricle — Pouch-like extension of atrium increasing chamber capacity.
  • Sinus venarum — Smooth area of right atrium's posterior wall.
  • Crista terminalis — Ridge separating smooth and rough parts of right atrium.
  • Trabeculae carneae — Muscular ridges in the ventricles.
  • Papillary muscles — Muscles anchoring the valve cusps via chordae tendineae.
  • Moderator band — Muscular band in right ventricle aiding contraction timing.
  • SA node — Sinoatrial node; initiates heartbeat.
  • AV node — Atrioventricular node; relays impulse to ventricles.
  • Cardiac plexus — Network of nerves supplying the heart.

Action Items / Next Steps

  • Review heart anatomy diagrams for chamber, valve, and vessel identification.
  • Practice tracing the flow of blood through the heart and associated vessels.
  • Read about the fetal circulation and developmental remnants (foramen ovale, ligamentum arteriosum).