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Vasodilator Medications Overview

Aug 28, 2025

Overview

This lecture reviews vasodilator medications, their indications, mechanisms, side effects, and nursing responsibilities in monitoring patients who receive these drugs.

Vasodilators: Definition and Examples

  • Vasodilators are medications that widen blood vessels (vasodilation).
  • Common vasodilators include nitroglycerin, minoxidil, and hydralazine.

Indications for Use

  • Treat angina by increasing coronary artery blood flow to the heart muscle.
  • Helpful in heart failure by reducing workload on the heart.
  • Prescribed for hypertension, coronary artery disease, pulmonary hypertension, and peripheral vascular disease.

Mechanism of Action and Effects

  • Vasodilators lower blood pressure by relaxing and widening blood vessels.
  • Decrease workload on the heart and vascular system by reducing resistance.

Side Effects

  • Can cause hypotension (low blood pressure) and orthostatic hypotension (dizziness when standing).
  • May lead to flushing, especially facial redness after nitroglycerin use.
  • Headaches (notably with nitroglycerin) are common.
  • Other side effects include nausea, vomiting, reflex tachycardia (increased heart rate), and edema (swelling).

Nursing Responsibilities

  • Monitor patientโ€™s blood pressure, heart rate, ECG, and watch for flushing or swelling.
  • Stay with patients with chest pain after administering vasodilators to assess pain changes.
  • Evaluate location, onset, quality, and frequency of chest pain.
  • Educate patients to change positions slowly to prevent fainting.

Key Terms & Definitions

  • Vasodilation โ€” widening of blood vessels.
  • Angina โ€” chest pain from reduced blood flow to the heart.
  • Orthostatic Hypotension โ€” drop in blood pressure when standing up.
  • Reflex Tachycardia โ€” increased heart rate in response to blood pressure drop.

Action Items / Next Steps

  • Monitor vital signs and ECG in patients on vasodilators.
  • Educate patients about moving slowly and reporting new or worsening chest pain.
  • Review additional pharmacology materials as assigned.