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Understanding COPD: Pathophysiology and Symptoms
Apr 28, 2025
COPD (Chronic Obstructive Pulmonary Disease) - NCLEX Review Part 1
Overview
COPD is a pulmonary disease causing chronic obstruction of airflow from the lungs.
Part 1 covers pathophysiology, signs, symptoms, types, and diagnosis of COPD.
Part 2 will cover medications and nursing interventions.
Definition
COPD leads to limited airflow due to chronic inflammation and narrowing of bronchioles.
Causes excessive mucus production, reducing oxygen intake and CO2 exhalation.
Key Points
Limited Airflow:
Inflammation and mucus block air pathways.
Difficulty Exhaling:
Loss of elasticity in alveolar sacs causes improper gas exchange.
Irreversible Condition:
Managed through lifestyle changes and medications.
Causes
Mainly environmental irritants (e.g., smoking, air pollution, occupational hazards).
Gradual onset, often noticed in middle age with symptoms like shortness of breath and chronic cough.
Types of COPD
Chronic Bronchitis (Blue Bloaters)
Characteristics:
Cyanosis (blue lips/skin), edema, right-sided heart failure.
Pathophysiology:
Inflammation and mucus production narrow airways.
Gas exchange is impaired, leading to hypoxemia and hyperinflation of lungs.
Diaphragm flattening causes increased use of accessory muscles.
Leads to respiratory acidosis and pulmonary hypertension.
Emphysema (Pink Puffers)
Characteristics:
Pink complexion, rapid breathing (puffing).
Pathophysiology:
Alveolar sacs lose elasticity, impairing gas exchange.
Air trapping in alveoli leads to lung hyperinflation.
Diaphragm flattening, increased use of accessory muscles.
Barrel chest appearance.
Hyperventilation compensates for low oxygen levels.
Signs and Symptoms (Mnemonic: LUNG DAMAGE)
L:
Lack of energy due to low oxygen.
U:
Unable to tolerate activity, severe shortness of breath.
N:
Poor nutrition due to energy spent on breathing.
G:
Abnormal gases (high CO2, low O2).
D:
Dry/productive cough (chronic).
A:
Accessory muscle use for breathing.
M:
Modified skin color (cyanosis to pink).
A:
Anterior-posterior diameter increase (barrel chest).
G:
Tripod position for easier breathing.
E:
Extreme dyspnea.
Complications
Heart disease and right-sided heart failure.
Spontaneous pneumothorax (lung collapse).
Increased risk of lung infections and cancer.
Diagnosis
Spirometry:
Measures lung capacity and exhalation speed.
FVC:
Forced Vital Capacity, indicates restrictive breathing.
FEV1:
Forced Expiratory Volume, indicates disease severity.
Next Steps
Review Part 2 for medications and nursing interventions.
Take the NCLEX review quiz for further practice.
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Full transcript