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Cell Connections and Communication Mechanisms

May 27, 2025

4.6 Connections between Cells and Cellular Activities - Biology 2e

Learning Objectives

  • Describe the extracellular matrix.
  • List examples of plant and animal cell communication.
  • Summarize roles of tight junctions, desmosomes, gap junctions, and plasmodesmata.

Extracellular Matrix of Animal Cells

  • Components: Proteins, primarily collagen, interwoven with proteoglycans.
  • Function: Holds cells together in tissue, facilitates cell communication.
  • Communication Mechanism:
    • Receptors on plasma membranes bind to molecules, altering the receptor's structure.
    • Changes in receptor structure affect microfilaments inside the cell.
    • This induces chemical signals that can alter protein production and cell activities.
  • Example: Blood clotting involves extracellular matrix communication to initiate clotting factors.

Intercellular Junctions

  • Cells communicate through direct contact.
  • Types:

Plasmodesmata (Plant Cells)

  • Channels between plant cell walls allowing transport of materials.
  • Connects cytoplasm of adjacent cells.
  • Facilitates transport from roots to leaves via vascular tissues (xylem and phloem).

Tight Junctions (Animal Cells)

  • Watertight seals between adjacent cells, held by proteins (claudins and occludins).
  • Prevents material leakage between cells.
  • Common in epithelial tissues, e.g., bladder lining.

Desmosomes (Animal Cells)

  • "Spot welds" between cells, connecting via cadherins to intermediate filaments.
  • Maintains cells in tissues that stretch (e.g., skin, heart).

Gap Junctions (Animal Cells)

  • Channels forming between adjacent cells for ions, nutrients transport.
  • Formed by connexons (six protein structure).
  • Critical in cardiac muscle for synchronized contraction.

Link to Learning

Citation

  • Authors: Mary Ann Clark, Matthew Douglas, Jung Choi
  • Publisher: OpenStax
  • Book Title: Biology 2e
  • Section URL: OpenStax Biology 2e

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