Lamotrigine: Key Information and Mnemonic

Overview

• Lamotrigine is used to treat:
  • Seizures
  • Bipolar disorder

Visual Mnemonic

• Memory Anchor: Limo
  • "Limo" sounds like Lamotrigine
  • Symbolizes lamotrigine's smooth ride as an anticonvulsant

Mechanism of Action

• Anticonvulsant: Prevents seizures by blocking voltage-gated sodium channels in the brain

Uses

• Seizure Treatment
  • Effective for a wide range of seizure types
  • Remember "anti-shake shocks" on the limo
• Bipolar Disorder Treatment
  • Particularly effective in treating the depressed phase
  • Symbol: Theater mask with happy and sad faces

Side Effects

• Severe Drug Rash: Stevens-Johnson Syndrome (SJS)
  • Blistering and peeling of the skin
  • Life-threatening
  • Risk is dose-dependent
  • Importance of titrating dose slowly
  • Report any signs of rash immediately
  • Mnemonic: Friend's rash at the masquerade party
• Sedation/Drowsiness
  • Due to CNS depression
  • Mnemonic: Sleeping limo driver

Conclusion

• Recap: Lamotrigine treats seizures and bipolar disorder
• Important Adverse Effects: SJS and sedation

Additional Resources

• Subscribe for more videos
• Access fact lists and interactive review images

Reminder

• Report signs of rash promptly to provider
• Understand dose titration to mitigate SJS risk

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These notes capture the key points and mnemonics presented in the lecture on lamotrigine. They help in memorizing the uses, side effects, and mechanisms of action associated with the medication.