Liver Function and Biliary System

May 27, 2024

Liver Function and Biliary System Lecture

Overview of Liver and Bile

  • Liver lobe and bile secretion discussed.
  • Bile flows through the common hepatic duct.

Components of Bile

  • Bile consists of:
    • Bile pigments: perform coloring function, not essential for bile function.
    • Bile salts: essential for emulsification, help in fat absorption.

Role of Bile Salts

  • Aid in emulsifying fats.
  • Convert fats into micelles for absorption in the ileum.

Biliary System

  • Liver synthesizes bile but does not store it.
  • Bile moves through the common hepatic duct.
  • First storage: bile ducts.
  • Next organ: gallbladder (stores bile until needed).

Gallbladder and Hormonal Control

  • Gallbladder's function: stores bile.
  • Hormone cholecystokinin (CCK) triggers bile release.
  • Procedure: Cholecystectomy (gallbladder removal).

Pathway of Bile

  • Bile synthesized in the liver.
  • Flows through common hepatic duct to bile duct, stored in gallbladder.
  • Hormone CCK causes gallbladder contraction, releasing bile.
  • Bile flows through the cystic duct into the common bile duct.
  • Final storage: common bile duct, releases bile into the digestive tract at the duodenum.

Function of Bile in Digestion

  • Bile emulsifies fats in the duodenum.
  • Bile salts and fats absorbed in the ileum.
  • Bile salts return to liver for reuse.

Key Processes and Pathways

  • Liver: bile synthesis.
  • Common Hepatic Duct: bile flow.
  • Gallbladder: bile storage.
  • CCK Hormone: triggers bile release.
  • Common Bile Duct: final bile storage and release into duodenum.
  • Duodenum: emulsification of fats.
  • Ileum: absorption of bile salts and fats.
  • Liver: recycle bile salts.

Summary

  • Biliary system: liver, ducts, gallbladder, and hormones work together for bile production, storage, release, and recycling.