Pharmacology and Practice Lecture Notes

Jul 20, 2024

Pharmacology and Practice Lecture

Introduction

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  • Focus: Two medications – combination hormonal contraceptives & terbutaline

Combination Hormonal Contraceptives

Components

  • Estrogen: Typically Ethylin Estradiol
    • Suppresses ovulation
    • Changes cervical mucus & uterine lining
    • Makes it difficult for sperm to reach egg/prevent implantation
  • Progesterone: Such as Leog Gestone
    • Prevents ovulation
    • Thickens cervical mucus to reduce pregnancy risk

Case Study: Emily

  • Patient: Emily, 25-year-old
  • Scenario: Gynecologist visit for contraceptive counseling
  • Recommendation: Oral contraceptive pill containing Ethylin Estradiol & Leog Gestone
  • Instructions:
    • Take one pill daily at the same time
    • Side effects: nausea, breast tenderness, breakthrough bleeding
    • Report any concerning symptoms
    • Use backup contraception during the first week and if any doses are missed
    • Regular follow-up for monitoring

Terbutaline

Usage

  • Medication used in OB to manage pre-term labor contractions
  • Bronchodilator: Relaxes smooth muscles in uterus, inhibits uterine contractions
    • Mnemonic: "Wait in line" with terbutaline to slow down contractions

Case Study: Sarah

  • Patient: Sarah, 28-year-old, 32 weeks pregnant
  • Scenario: Labor and delivery unit with contractions, diagnosed with pre-term labor
  • Treatment:
    • IV infusion of terbutaline
    • Gradual dose increase until contractions subside or max dose is reached
    • Continuous monitoring of vital signs (heart rate, blood pressure, fetal heart rate)
    • Switch to oral terbutaline tablets after 24 hours

Key Point

  • Terbutaline is used as a tocolytic to suppress premature labor and delay pre-term birth

Conclusion

  • Summary: Two medications – hormonal contraceptives for birth control & terbutaline for pre-term labor management
  • Emphasis on the importance of understanding pharmacology for safe, effective patient care
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