lorazapam also known by the trade name Adavan lorazapam is indicated for the treatment of anxiety seizures and fation lorazapam works via General CNS depression by potentiating inhibitory neurotransmitters the therapeutic classification of lorazapam are anesthetic adjuncts an anti-anxiety agent and a sedative Hypno the pharmacologic class is a benzo dipene special considerations for nursing include using caution in those with COPD and sleep apnea as it may have an impact on respiratory rate concurrent alcohol use should be discouraged as it may cause excessive sedation in cases of Overdose flumazenil known by the trade name romazicon should be used however this use should be very cautious as rapid reversals of benzo diazines may lead to seizures lorazapam may cause apnea Cardiac Arrest Broc cardia and hypotension and use should be cautious in conjunction with other CNS depressants when given IV Administration should be slow and the drug should be diluted to decrease compli ation of sudden sedation or any local effects such as fitis it is important to know that the IV formulation of lpam does contain propylene glycol and at small doses this is generally not an issue however in those receiving very high doses of lorazapam or those receiving IV lorazapam with great frequency as well as those with significant renal impairment who cannot clear propylene glycol properly there may be accumulation in the body of propylene glycol leading to toxicity this can lead to lactic acidosis seizures and respiratory depression and in rare cases death this has been another episode of the nursing.com medmaster podcast my name is John H rncc alumnus and I want to give you our free download of the 50 most commonly prescribed medications to get that free download just go to nursing.com sl50 meds that's 50 nursing.com sl50 meds we love you guys we want you to succeed that's why we provide clear concise and visual supplement for nursing school and the clinical floor we love you guys go out and be your best s happy nursing