everybody welcome back to drug talk as always i'm your host garrett campbell in today's video we're going to be discussing a medication known as linezolid or xivoxian for a brand name and before we talk about the medication itself just keep in mind that this channel is for information purposes only and not to be used as a source for recommendations for your personal health care during this presentation we'll discuss the mechanism of action or how this medication works indications or reasons we would prescribe lines only to a patient followed by contraindications or reasons we would not be able to prescribe this medication i'll touch on two examples of dosing and then finish it off with side effects with percentages i've put together some slides to go over this information let's jump right into it so the first thing to discuss here be the mechanism of action or how this medication works though linezolid inhibits bacterial reproduction of aerobic gram-positive bacteria and certain gram-negative anaerobic bacteria it selectively binds to a site on the 23s ribosomal rna of the 50s subunit thereby preventing initiation of complex formation with the 70s ribosomal subunit in terms of indications or reasons you would prescribe line as a lead to a patient we may see used for both community as well as hospital acquired pneumonia we may see used to treat an infection of the skin or subcutaneous tissue the nasal lid can be used for mrsa infections as well as vancomycin resistant enterococcus fascium infections with respect to contraindications or reasons we would not be able to prescribe linezolid to a patient well first of all we wouldn't give this medication to a patient to add a hypersensitivity to a nasolid or to any other component of the formulation also this medication would not be used with a monoamine oxidase inhibitor or within two weeks of taking a monoamine oxidase inhibitor for example phenylsine now for some examples of dosing with melanozoid so in the treatment of community acquired pneumonia we may see 600 milligrams intravenously or orally every 12 hours for 10 to 14 days or for 7 to 21 days with an mrsa associated infection in the treatment of an infection of the skin or subcutaneous tissue we may see 400 milligrams orally every 12 hours for 10 to 14 days as with all medications there are some side effects or adverse reactions that patients may experience while using lynn as a lid so i'll go over some of those here now some common side effects would be diarrhea coming in at eight percent nausea coming in at five to six percent and two to four percent of patients may experience vomiting five and a half to eight and a half may experience a headache more serious but more rare side effects would be lactic acidosis clostridium difficile infection as well as milo suppression all right everybody that's all we're going to talk about today with leneza lid or xivoxam as always i'm very thankful you took the time you mind watching my videos if you found the information valuable you'd like to help grow this channel remember you can like the videos share the videos most importantly subscribe to the youtube channel and there's also some links in the description you can check out as well for today take care [Music]