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Overview of Brain Anatomy and Functions

May 4, 2025

Lecture Notes: Brain Anatomy and Functions

Ventral View of the Frontal Lobe

  • Landmarks:
    • Olfactory Tracks and Bulbs on the ventral surface.
    • Orbital Frontal Cortex: deals with emotions, rich connections with the amygdaloid nucleus (amygdala).
    • Amygdala: Handles emotions, predominantly fear.
  • Prefrontal Cortex:
    • Role in inhibition, decides what to say/not to say.
    • Reduction of inhibitory fibers with aging can lead to less social inhibition.

Parietal Lobes

  • Central Sulcus:
    • Post Central Gyrus: Primary sensory area, areas 3, 1, 2.
    • Sensory modalities: Taste, touch, pressure, pain, temperature, kinesthetic sense.
  • Inferior Parietal Cortex:
    • Area 40 (Supramarginal Gyrus):
      • Lesions here can cause asterognosis (inability to recognize objects by touch).
    • Area 39 (Angular Gyrus):
      • Integrates information from visual, auditory, and general sensory.
      • Associated with logic and math.
  • Superior Parietal Lobe:
    • Areas 5 and 7.
    • Lesions can lead to neglect syndrome on the opposite side of the body (e.g., right lesion causes left neglect).

Occipital Lobe

  • Visual Cortex: Defined by preoccipital notch and parietal-occipital fissure.
    • Area 17 (Primary Visual Cortex):
    • Areas 18 and 19 (Visual Association Cortex): Integrates visual information and memory.
    • Large representation on the medial surface.

Temporal Lobe

  • Auditory Cortex:
    • Area 41 (Primary Auditory Cortex):
    • Area 42 and 22 (Auditory Association Cortex):
    • Wernicke's Area: Understanding of words, traditionally in the posterior superior temporal gyrus but can vary.

Other Key Concepts

  • Hippocampus and Hypothalamus: Involved in emotion and memory.
  • Broca's Area (44 and 45): Involved in speech production.
  • Insula: Potentially involved in speech and visceral functions.
  • Corpus Callosum: Connects the two hemispheres. Some individuals may lack it (agenesis).
  • Cell Types in Cortex:
    • Pyramidal cells and stellate cells contribute to cortical function.

Functional Pathways and Syndromes

  • Corticospinal Tract: Carries voluntary motor signals from area 4 and adjacent areas (3, 1, 2, 5).
  • Neglect Syndrome: Results from right superior parietal lesions, affects awareness of the left body side.
  • Stereognosis: The ability to recognize objects by touch, linked to specific cortical areas.

Experimental Insights

  • Lesions and Cognitive Functions:
    • Studies on Einstein's brain focused on prefrontal and angular gyrus areas.
    • Distribution of Wernicke's area may vary among individuals with different intelligence levels.
  • Neuroplasticity:
    • Dendritic branching increases with higher education levels.

Miscellaneous

  • Blood Supply:
    • Posterior cerebral artery supplies visual cortex and part of the inferior temporal lobe.
  • Paramal and Stellate Cells: Major cell types in the cortex.
  • Functional Anatomy and Educational Implications:
    • Knowing specific brain areas is crucial for neurological and educational studies.
  • Visual Cortex Representation:
    • Extensive representation on the medial surface of the brain.