General Pharmacology Lecture Notes

Jun 26, 2024

Chapter 18: General Pharmacology

EMS Medications

  • Medications that EMTs can administer:
    • Aspirin
    • Oral Glucose
    • Oxygen
    • Activated Charcoal
    • Naloxone (Narcan)

Aspirin

  • Indication: Suspected chest pain due to myocardial infarction (heart attack)
  • Action: Reduces clotting factors in the blood

Oral Glucose

  • Indication: Diabetic emergencies with low blood sugar
  • Action: Raises blood sugar levels

Oxygen

  • Action: Administered under medical direction or standing orders
  • Common Usages: For patients under EMS care requiring oxygen

Activated Charcoal

  • Action: Absorbs poisons in the body, preventing absorption into the bloodstream

Naloxone (Narcan)

  • Indication: Narcotic overdoses
  • Action: Binds to opioid receptors, blocking narcotics like heroin, morphine, fentanyl
  • Side Effects: Severe vomiting, irritability

Assisting with Medications

  • EMTs can assist with:
    • Metered Dose Inhalers (MDIs)
    • Nitroglycerin
    • Epinephrine

Metered Dose Inhalers (MDIs)

  • Common Medication: Albuterol
  • Usage: Asthma, emphysema, chronic bronchitis
  • Side Effects: Increased heart rate, jitteriness

Nitroglycerin

  • Indication: Chest pain
  • Form: Spray (400 micrograms) or tablets (0.4 mg)
  • Action: Vasodilation of blood vessels
  • Contraindications: Low blood pressure, concurrent use of erectile dysfunction drugs
  • Side Effects: Drop in blood pressure, check BP 5 minutes post-administration

Epinephrine Auto-Injectors

  • Indication: Severe allergic reactions (anaphylaxis)
  • Action: Vasoconstrictor, relaxes smooth muscles in airways
  • Side Effects: Increased heart rate, blood pressure
  • Administration: EMTs in Colorado with IV cert. can draw and inject directly

Force Protection Medications

  • Example: Nerve agent antidotes (e.g., 2-PAM)
  • Storage: Stored centrally, not on ambulances

Medication Information

  • Names: Generic, chemical, trade names
  • Indications: Conditions for giving the drug
  • Contraindications: When not to give the drug
  • Side Effects: Mild effects (e.g., BP drop from nitroglycerin)
  • Untoward Effects: Severe effects (e.g., severe headache)

Forms of Medications

  • Compressed Powders/Tablets: Aspirin
  • Liquids: Epinephrine, Albuterol
  • Gels: Oral Glucose
  • Suspensions: Activated Charcoal
  • Fine Powders: Albuterol
  • Mist/Gases: Oxygen
  • Sublingual Spray: Nitroglycerin

Medication Administration

  • Understanding Medications:
    • Indications
    • Contraindications
    • Side Effects
    • Dosage
    • Effectiveness

Routes of Administration

  • Oral: Swallowed (e.g., activated charcoal, oral glucose, aspirin)
  • Rectal: Absorbed through digestive tract
  • Sublingual: Under the tongue (e.g., nitroglycerin)
  • Inhaled: Breathed into lungs (e.g., oxygen)
  • Intranasal: Sprayed into nose (e.g., Narcan)
  • Intravenous (IV): Into vein
  • Intramuscular (IM): Into muscle (e.g., epinephrine)
  • Subcutaneous: Under the skin
  • Intraosseous: Into bone
  • Endotracheal: Into trachea

Pharmacodynamics

  • Study of medication effects on the body
  • Factors Influencing Drug Action: Kidney/liver disease, other medications

Documentation

  • Include: Doctor’s order, route of administration, dosage, patient’s reaction
  • Mistakes: Report and document all actions taken to rectify errors

IV Therapy

  • Saline Lock/Heparin Lock: For quick medication administration
  • IV Bags: Connected to saline lock
  • Tubing: Includes drip chamber, regulator, and ports for medication
  • Flow Issues: Check tubing, constricting bands, IV site, and for kinks