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Separation Methods and Principles

Aug 25, 2025

Overview

This lecture discusses the principles and common methods of separating mixtures based on physical properties, highlighting their applications in daily life and industry.

Principles of Mixture Separation

  • A mixture contains two or more substances combined physically.
  • Separation is needed to obtain pure substances from mixtures.
  • Separation relies on differences in physical properties like state, particle size, melting point, boiling point, magnetism, and solubility.

Common Methods of Separation

  • Filtration is used to separate insoluble solids from liquids by particle size differences.
  • Centrifugation separates very fine solid particles from liquids, especially useful for small quantities.
  • Distillation separates liquids based on differences in boiling points.
  • Chromatography separates and identifies substances in a mixture based on their movement through a medium.
  • Sublimation separates mixtures where one solid can convert directly to gas, leaving others behind.

Everyday and Industrial Applications

  • Filtration is commonly used for water purification.
  • Distillation is used in daily life and industry to refine and separate liquids (e.g., alcohol, petroleum).
  • Centrifugation is used in medical labs to separate blood components.
  • Chromatography is used for urine drug tests and to analyze dyes.

Key Terms & Definitions

  • Mixture โ€” a physical combination of two or more substances.
  • Filtration โ€” separation of insoluble solids from liquids using a filter.
  • Centrifugation โ€” separation by spinning to sediment fine particles.
  • Distillation โ€” separation of liquids by differences in boiling points.
  • Chromatography โ€” separation and identification of mixture components based on movement in a medium.
  • Sublimation โ€” separation relying on a solid changing directly to gas, leaving non-subliming solids.

Action Items / Next Steps

  • Review each separation method and note which physical property it exploits.
  • Prepare examples of each method for class discussion.
  • Complete assigned reading on real-world applications of mixture separation.