Cardiogenic Shock Lecture
Anatomy of the Heart
- Compartments: Right atrium, right ventricle, left atrium, left ventricle.
- Function: Right heart pumps blood to the lungs; left heart pumps oxygenated blood to the body.
Heart Function and Failure
- Cardiac Output: Essential for delivering oxygen and nutrients.
- Failure Causes:
- Valvular Problems: Damaged/narrowed aortic outflow tract
- Arrhythmias: Disrupted electric conduction
- Ventricular Wall Stiffness: Limits contractility
- Heart Attacks (MIs): Major cause of cardiogenic shock
Symptoms of Heart Failure
- Pulmonary Congestion: Blood backs up into the lungs, causing difficulty in breathing and a productive cough.
- Jugular Venous Distention (JVD): Blood backs up into the venous system, distending the jugular vein.
- Angina: Chest pain due to oxygen deprivation.
- Organ Dysfunction: Decreased urine output, organ failure due to inadequate oxygenation.
- Cool Skin: Blood diverted away from the skin to vital organs.
Diagnosing Cardiogenic Shock
- Typical Labs:
- Serum Lactate & ABG: Assess oxygenation and tissue utilization.
- Troponins: Check for myocardial damage (e.g., heart attack).
- Chest X-ray: Identify pulmonary congestion.
- EKG: Identify arrhythmias or heart attacks.
- Echocardiogram: Assess heart contractility.
- Important Measures:
- PCWP: Elevated >18mm Hg (backup pressure in pulmonary arteries).
- Cardiac Index: <2.2 L/min/m² (standardized cardiac output).
Treatment of Cardiogenic Shock
- Oxygen Support: Provide to ensure tissue oxygenation.
- Cardiovascular Support:
- Increase Systemic Vascular Resistance: Use vasopressors (e.g., norepinephrine, epinephrine).
- Improve Heart Contractility: Medications to enhance contraction.
- Correct Underlying Issues:
- Revascularization: Restore blood flow in occluded vessels.
- Valve Repair/Replacement: Fix or replace faulty valves.
- Heart Transplant: In severe cases, replace the heart.
Key Takeaway
Cardiogenic shock is a condition where the heart fails to pump sufficient blood, leading to poor oxygen delivery to the body's tissues and organs.