Cardiogenic Shock Lecture Notes

May 29, 2024

Cardiogenic Shock Lecture

Anatomy of the Heart

  • Compartments: Right atrium, right ventricle, left atrium, left ventricle.
  • Function: Right heart pumps blood to the lungs; left heart pumps oxygenated blood to the body.

Heart Function and Failure

  • Cardiac Output: Essential for delivering oxygen and nutrients.
  • Failure Causes:
    • Valvular Problems: Damaged/narrowed aortic outflow tract
    • Arrhythmias: Disrupted electric conduction
    • Ventricular Wall Stiffness: Limits contractility
  • Heart Attacks (MIs): Major cause of cardiogenic shock

Symptoms of Heart Failure

  • Pulmonary Congestion: Blood backs up into the lungs, causing difficulty in breathing and a productive cough.
  • Jugular Venous Distention (JVD): Blood backs up into the venous system, distending the jugular vein.
  • Angina: Chest pain due to oxygen deprivation.
  • Organ Dysfunction: Decreased urine output, organ failure due to inadequate oxygenation.
  • Cool Skin: Blood diverted away from the skin to vital organs.

Diagnosing Cardiogenic Shock

  • Typical Labs:
    • Serum Lactate & ABG: Assess oxygenation and tissue utilization.
    • Troponins: Check for myocardial damage (e.g., heart attack).
    • Chest X-ray: Identify pulmonary congestion.
    • EKG: Identify arrhythmias or heart attacks.
    • Echocardiogram: Assess heart contractility.
  • Important Measures:
    • PCWP: Elevated >18mm Hg (backup pressure in pulmonary arteries).
    • Cardiac Index: <2.2 L/min/m² (standardized cardiac output).

Treatment of Cardiogenic Shock

  1. Oxygen Support: Provide to ensure tissue oxygenation.
  2. Cardiovascular Support:
    • Increase Systemic Vascular Resistance: Use vasopressors (e.g., norepinephrine, epinephrine).
    • Improve Heart Contractility: Medications to enhance contraction.
  3. Correct Underlying Issues:
    • Revascularization: Restore blood flow in occluded vessels.
    • Valve Repair/Replacement: Fix or replace faulty valves.
    • Heart Transplant: In severe cases, replace the heart.

Key Takeaway

Cardiogenic shock is a condition where the heart fails to pump sufficient blood, leading to poor oxygen delivery to the body's tissues and organs.