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Arpan - Understanding Chiari Malformation and Symptoms

Mar 31, 2025

Chiari Malformation

Overview

  • Definition: Chiari malformation is a brain condition where the cerebellum is displaced downward through the foramen magnum into the upper spinal canal.
  • Consequences: Can lead to severe problems such as increased pressure on the brainstem and blockage of cerebrospinal fluid flow, potentially causing obstructive hydrocephalus.

Anatomy

  • Normal Anatomy:
    • Skull
    • Cerebellum
    • Brain Stem
    • Spinal Cord
    • Foramen Magnum
  • Chiari Malformation:
    • Cerebellar tonsils descend through the foramen magnum.

Types of Chiari Malformation

  • Type 1:
    • Most common.
    • Congenital, usually present at birth.
    • Characterized by the downward descent of the cerebellar tonsil.
  • Type 2 (Arnold-Chiari Malformation):
    • Associated with myelomeningocele, a feature of spina bifida.
    • Involves downward displacement of cerebellum, brainstem, and fourth ventricle.
    • Leads to obstructive hydrocephalus.
  • Types 3 and 4: Less common.

Symptoms

  • Headaches, often exacerbated by coughing or straining.
  • Neck pain.
  • Nausea and vomiting.
  • Balance and coordination problems.
  • Dizziness.
  • Muscle weakness.
  • Vision and hearing disturbances.
  • Fine motor skill difficulties.
  • Difficulty with swallowing or speaking.
  • Symptoms vary among individuals but some are common.

Diagnosis

  • MRI: Used to assess the extent of cerebellar tonsil descent or herniation.
  • Type 2 Features:
    • Descent of cerebellar tonsils, cerebellum, and brainstem.
    • Associated with myelomeningocele.

Epidemiology

  • Affects individuals of all ethnicities.
  • Greater prevalence in females, potentially due to genetic factors.

Treatment

  • Management:
    • Physiotherapy
    • Pain medications
    • Surgery for severe cases

Additional Resources

  • Further notes and flashcards available on Instagram and Facebook pages.
  • Support available through social media platforms.