Overview of Malignant Salivary Gland Diseases

Apr 27, 2025

Oral Pathology: Malignant Salivary Gland Diseases

Introduction

  • Presenter: Ryan
  • Topic: Malignant diseases of salivary gland origin
  • Focus: Classification by microscopic appearance
  • Common Location: Most common on the palate

Comparison with Benign Tumors

  • Previously discussed benign tumors:
    • Pleomorphic adenoma: Most common on the palate and parotid gland
    • Warthin's tumor: Most common on the parotid gland
  • Malignant tumors differ as they are most common on the palate

Malignant Salivary Gland Diseases

Mucous Epidermoid Carcinoma

  • Most Common salivary gland malignancy
  • Composition: Mucous and epithelial cells
  • Location: Commonly found on the palate
  • Key Point: Remember as the most common salivary malignancy

Polymorphous Low-Grade Adenocarcinoma (PLGA)

  • Second Most Common salivary gland malignancy for minor glands
  • Meaning: "Adeno" refers to gland
  • Location: Also commonly found on the palate
  • Key Point: Known as the second most common salivary gland malignancy

Adenoid Cystic Carcinoma

  • Characteristic Feature: Cribriform or "Swiss cheese" microscopic pattern
    • Appearance: Empty spaces or holes observed under a microscope
  • Effect on Other Tissues: Can also affect breast tissue with a similar microscopic appearance
  • Survival Rates:
    • 5-year survival rate: 70%
    • 15-year survival rate: 10%
  • Key Point: Important for board exams due to its distinctive pattern and prognosis

Conclusion

  • Summary: Overview of malignant salivary gland diseases focusing on the most common types and their characteristics
  • Call to Action: Like and subscribe for more oral pathology content
  • Thank You: Gratitude for viewers' participation