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Essential Guide to Parenteral Nutrition

Apr 29, 2025

Parenteral Nutrition (PN) Overview

Definition and Purpose

  • Parenteral Nutrition (PN) is a medical and nutritional treatment.
  • Also known as Total Parenteral Nutrition (TPN).
  • Administered when a patient cannot consume food orally due to:
    • Illness
    • Surgery
    • Non-functioning stomach or bowel.
  • Can supplement nutrition when oral or tube feeds are insufficient.

Administration

  • Prepared by the pharmacy department in certain hospitals.
  • Administered in a specialized bag through an intravenous (IV) catheter using a pump.

Hospitals Preparing PN

  • Within Horizon Health Network:
    • Dr. Everett Chalmer Regional Hospital
    • Miramichi Regional Hospital
    • Moncton Hospital
    • Saint John Regional Hospital
    • Upper River Valley Hospital
  • Saint John Regional Hospital also prepares home PN for eligible patients.

Components of Parenteral Nutrition

  • Nutrients included:
    • Protein (amino acids)
    • Carbohydrates (dextrose)
    • Fat (lipids/fat emulsions)
    • Electrolytes: sodium, potassium, calcium
    • Vitamins and Minerals

PN Team

  • Includes:
    • Specialist doctors (gastroenterologist, surgeon, pediatrician)
    • Nurses
    • Dieticians
    • Pharmacists
  • Responsible for ensuring the PN meets individual needs.
  • Available for support and to address questions or concerns.

Preparation Process

  • Prepared in a sterile room by pharmacy staff.
  • Use of a compounder machine for automatic preparation.
    • Order entered into a compounder computer program.
    • Label printed, compared, and scanned to ensure accuracy.
  • Some hospitals use premixed bags, carefully selected by the PN team.
  • Double-checked by pharmacy team before administration.

Storage and Administration

  • Stored in a refrigerator on the nursing unit.
  • Typically administered continuously over 24 hours.
  • Lipids may be administered separately over shorter periods (e.g., 12 hours).

Monitoring and Adjustments

  • Regular review of medical conditions and blood work by the PN team.
  • Adjustments made to PN ingredients as necessary.
  • Monitoring for complications (e.g., infections, changes in blood work, IV access issues).

Discontinuation

  • Most patients do not require PN after hospital discharge.
  • PN stopped once adequate nutrition is achieved through oral intake or feeding tube.
  • PN team discusses reasons for stopping with patients if necessary.

Support

  • Continuous support from the PN team available for any queries or issues related to PN.
  • Encouragement to consult with physician, nurse, dietician, or pharmacist for concerns.