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Biomolecules Overview

Sep 7, 2025

Overview

This lecture covers the four major biomolecules—carbohydrates, proteins, nucleic acids, and lipids—highlighting their building blocks, bonding types, examples, elements, and primary functions in living organisms.

Carbohydrates

  • Made of monosaccharides (simple sugars) joined by glycosidic bonds.
  • Examples: glucose (monosaccharide), maltose (disaccharide), starch and cellulose (polysaccharides).
  • Composed of carbon, hydrogen, and oxygen.
  • Serve as the main short-term energy source in cells.
  • Provide structural support (e.g., cellulose in plants, chitin in fungi).
  • Two main types: storage polysaccharides (starch, glycogen) and structural polysaccharides (cellulose, chitin).

Proteins

  • Built from amino acids linked by peptide bonds.
  • Each amino acid contains a central carbon, amino group (NH2), carboxyl group (COOH), hydrogen, and variable side chain.
  • Examples: insulin, collagen, keratin, hemoglobin.
  • Elements: carbon, hydrogen, oxygen, nitrogen, sometimes sulfur.
  • Functions include acting as enzymes, structural support, defense (antibodies), hormones, and oxygen transport.

Nucleic Acids

  • Composed of nucleotides joined by phosphodiester bonds.
  • Each nucleotide has a sugar, phosphate group, and nitrogenous base.
  • DNA (double-stranded) and RNA (single-stranded) are principal examples.
  • Elements: carbon, hydrogen, oxygen, nitrogen, phosphorus.
  • Store and transmit genetic information; RNA acts as a mediator in protein synthesis.
  • DNA is usually the genetic material, except in some viruses where RNA serves this role.

Lipids

  • Made from fatty acids and glycerol joined by ester bonds; no true monomeric unit.
  • Examples: fats, oils, waxes.
  • Elements: carbon, hydrogen, oxygen; hydrophobic in nature.
  • Main long-term energy storage, insulation, and organ protection.
  • Major component of biological membranes (phospholipids).
  • Source of hormones like steroids (e.g., estrogen, androgen).

Key Terms & Definitions

  • Monosaccharide — Simple sugar unit of carbohydrates.
  • Glycosidic Bond — Link joining two monosaccharides.
  • Amino Acid — Building block of proteins.
  • Peptide Bond — Link joining two amino acids.
  • Nucleotide — Building block of nucleic acids.
  • Phosphodiester Bond — Link joining two nucleotides via phosphate groups.
  • Ester Bond — Link between glycerol and fatty acids in lipids.
  • Polysaccharide — Multiple monosaccharides joined together.

Action Items / Next Steps

  • Review the properties and functions of each biomolecule.
  • Refer to detailed videos or resources for deeper understanding of individual biomolecules if needed.