Overview
This lecture explains anaerobic cellular respiration, focusing on the processes and significance of glycolysis and fermentation in the absence of oxygen or mitochondria.
Cellular Respiration Overview
- Aerobic respiration uses glucose, glycolysis, the Krebs cycle, electron transport chain, and requires mitochondria and oxygen.
- Glycolysis breaks down glucose to pyruvate, netting 2 ATP.
- Krebs cycle produces 2 more ATP and releases COâ‚‚.
- Most ATP (32-34) is generated in the electron transport chain with oxygen as the final electron acceptor.
Anaerobic Cellular Respiration
- Occurs when there is no oxygen or no mitochondria.
- Consists of glycolysis followed by fermentation.
- Glycolysis alone cannot continue without regenerating NAD+ from NADH.
- Two types of fermentation: lactic acid fermentation and alcoholic fermentation.
Lactic Acid Fermentation
- Performed by animals and some bacteria after glycolysis.
- Pyruvate is converted into lactate (lactic acid), regenerating NAD+ for continued glycolysis.
- No additional ATP is produced in fermentation; ATP comes only from glycolysis.
- Builds up lactate in muscles during intense exercise, causing pain and fatigue.
- Lactate is later broken down using oxygen after exercise.
- Bacteria use lactic acid fermentation to make products like yogurt.
Alcoholic Fermentation
- Occurs in yeast and some bacteria.
- Pyruvate is converted into ethyl alcohol (ethanol) and COâ‚‚, regenerating NAD+.
- Used in brewing and baking; alcohol accumulation eventually kills the yeast.
- COâ‚‚ produced causes bubbles in beer, champagne, and bread.
Key Terms & Definitions
- Anaerobic respiration — cellular respiration that occurs without oxygen or mitochondria.
- Glycolysis — first step in breaking down glucose to pyruvate, netting 2 ATP.
- Fermentation — process that regenerates NAD+ from NADH, allowing glycolysis to continue in anaerobic conditions.
- Lactic acid fermentation — fermentation process producing lactate and regenerating NAD+.
- Alcoholic fermentation — fermentation producing ethanol and CO₂ while regenerating NAD+.
Action Items / Next Steps
- Review related lecture/videos on aerobic respiration, mitochondria, and associated processes as needed.