Lecture Notes: Liver Anatomy and Blood Supply

Introduction

• Channel Promotion: Subscribe to Aran Biology and Medicine for latest videos.
• Social Media Engagement: Join the Forman group on Facebook to ask and answer questions, post artworks, and more.
• Video Focus: Liver anatomy and its blood supply.

General Facts About the Liver

• Largest internal organ in the body.
• Weight: 1.2 to 1.6 kilograms in healthy adults.
• Location: Right side of the body, under the lower ribs.
• Structure: Consists of four lobes of unequal size.

Proximity to Other Organs

• Gallbladder: Located under the liver; connects via bile duct and cystic duct, part of the bile system.
• Stomach: Lies to the left of the liver.

Blood Supply to the Liver

• Oxygen and Nutrient Requirements: Liver needs both oxygen and nutrients, supplied by two main sources.

Oxygenated Blood Supply

• Hepatic Artery: Delivers oxygenated blood from the heart to the liver.
• Aorta: The artery from the heart supplies other organs like the spleen and intestines.

Deoxygenated Blood Supply

• Portal Vein: Carries deoxygenated, nutrient-rich blood from the stomach, spleen, and intestines to the liver.
• Hepatic Vein: Carries deoxygenated blood away from the liver to the heart.

Detailed Blood Flow

• Hepatic Artery: Supplies about 25% of the liver's blood supply.
• Portal Vein: Supplies about 75% of the liver's blood supply.

Liver Structure and Organization

• Lobules: Hexagonal units within the liver containing hepatic cells.
• Central Vein: Located at the center of each lobule, connects to the hepatic vein.
• Portal Triads: Consist of portal vein, bile duct, and hepatic artery.

Pathways

• Blood Flow: Portal vein and hepatic artery deliver nutrients and oxygen to hepatocytes, respectively.
• Bile Production: Bile produced is transported to the gallbladder via bile ducts.

Special Cells and Functions

• Kupffer Cells: Hepatic macrophages important for the immune system.

Summary

• Liver Functionality: Integration of blood supply and nutrient distribution within the liver's structural units.
• Next Topic: Physiology of the liver.

End of notes. For further study, review this summary and watch the next video on liver physiology.